51) Craniopharyngioma clinical trials and research updates

I periodically check on research that may pertain to craniopharyngioma and/or hypothalamic obesity and am pleased when I learn about current clinical trials or recently published research.

In case you are interested, here are some actively recruiting studies on craniopharyngioma.

Stanford University is recruiting subjects (ages 6-30) to study social impairments among those with pituitary and hypothalamic tumors/disorders. http://med.stanford.edu/parkerlab/research/Biomarkers-of-Social-Impairments-in-Individuals-with-Hypothalamic-Pituitary-Disorders.html

Children's Hospital of Philadelphia is recruiting craniopharyngioma subjects (ages 10-21) with HO for an oxytocin study.
https://clinicaltrials.gov/ct2/show/NCT02849743

Seattle Children's Hospital is recruiting craniopharyngioma subjects (ages 10-25) with HO for an Exenatide study.  The study is also taking place and recruiting in Minneapolis and Nashville.
https://clinicaltrials.gov/ct2/show/NCT02664441

Klinikum Oldenburg (Germany) is recruiting craniopharyngioma subjects (diagnosed before age 18) to study quality of life following various therapeutic interventions.
https://clinicaltrials.gov/show/NCT01272622

Dr. Hoong Wei-Gan  et al. (London Great Ormond Street Hospital for Children) presented a poster on oxytocin deficiency in hypothalamic obesity at an Endocrine Society conference in April, 2016:
http://abstracts.eurospe.org/hrp/0086/hrp0086P1-P738.htm

Dr. Gan is in the midst of conducting research on oxytocin and vasopressin deficiency among hypothalamic brain tumor survivors with HO and without HO to see if in fact those with HO have significantly lower levels oxytocin and vasopressin than those without HO.  Finding a significant deficiency of oxytocin in the cohorts with HO would certainly suggest replacing the hormone in hypothalamic brain tumor survivors with HO. I am unable to find any indication of active recruitment so I assume his study is underway and closed for recruitment at the moment.

Dr. Elizabeth Lawson is the PI for an oxytocin trial for (non-cranio, BMI=30 to 50) obese adults at Massachusetts General Hospital: https://clinicaltrials.gov/ct2/show/NCT03043053

And last but not least, here is a very important and rare paper (abstract only) on craniopharyngioma and oxytocin, hot off the presses, published in September, 2016:
https://www.ncbi.nlm.nih.gov/pubmed/27585663